TUBERCLE ANTITOXIN OR ANTI-TUBERCULIN.

Inhibition of Tuberculin Skin Hypersensitivity in Guinea Pigs by Injection of Tuberculin and Intact Tubercle Bacilli during Fetal Life

FEMALE GUINEA PIGS WERE SUBJECTED TO LAPAROTOMY AT DIFFERENT STAGES OF PREGNANCY, AND THEIR FETUSES INJECTED THROUGH THE UTERINE WALLS WITH ONE OF THE FOLLOWING PREPARATIONS: Old Tuberculin, tubercle bacilli of the BCG strain killed by heat or exposure to phenol, and living BCG. A large number of the animals injected in utero with Old Tuberculin failed to develop skin hypersensitivity to P.P.D....

Endoribonuclease type II toxin-antitoxin systems: functional or selfish?

Most bacterial genomes have multiple type II toxin-antitoxin systems (TAs) that encode two proteins which are referred to as a toxin and an antitoxin. Toxins inhibit a cellular process, while the interaction of the antitoxin with the toxin attenuates the toxin's activity. Endoribonuclease-encoding TAs cleave RNA in a sequence-dependent fashion, resulting in translational inhibition. To account ...

Toxin-Antitoxin Pairs in Bacteria Killers or Stress Regulators?

Plasmid toxin-antitoxin systems, which kill daughter cells that fail to inherit the plasmid genome, have chromosomal homologs in eubacteria and archaea. In this issue of Cell, Pederson et al. show that the E. coli RelE toxin cleaves mRNA in the ribosomal A site, potentially allowing it to function as a stress regulator during amino acid starvation.

Tuberculin in Ophthalmology Tuberculin in Ophthalmology

Tuberculin Test

  در ایالات متحده حدود ۱۵ میلیون نفر آلوده به میکروب سل می باشند و هر سال ۳۰ هزار مورد جدید گزارش می شود. انتظار می رود تا سال ۲۰۰۰ این رقم به ۵۰۰۰۰ نفر در سال برسد. تست مانتو نسبت به تست چند سوزنی که قبلاً بسیار متداول بود، بمراتب دقیق تر است و بهمین دلیل به عنوان یک روش انتخابی برای غربالگری سل شناخته شده است. امروزه این تست اولین اقدام برای اثبات عفونت کلینیکی بوده و در صورتی که بطور دقیق ا...